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Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines.
Agata Tarczykowska
,
Niklas Engström
,
Darja Dobermann
,
Jonathan Powell
,
Nathalie Scheers
Apr 17, 2023
We previously showed that two iron compounds that are orally ingested by humans, namely ferric EDTA and ferric citrate, can induce an oncogenic growth factor (amphiregulin) in human intestinal epithelial adenocarcinoma cell...
Iron
IL-6
IGF1R
COX-2
amphiregulin
IFNGR1
ferric pyrophosphate
Cell Line
Humans
Adenocarcinoma
Iron Compounds
Ferric Compounds
Salts
Edetic Acid
Interleukin-6
Iron Chelating Agents
Signal Transduction
STAT Transcription Factors
Cyclooxygenase 2
Janus Kinases
Biomarkers
Published by:
International journal of molecular sciences